Abstract Background Surgery represents the only curative treatment option for pancreatic ductal adenocarcinoma (PDAC), but recurrence in more than 85% of patients limits the success of curative-intent tumor resection.Neural invasion (NI), particularly the spread of tumor cells along nerves into extratumoral regions of the pancreas, constitutes a we
The Never in Mitosis A (NIMA) kinase (the founding member of the Nek family of kinases) has been considered a mitotic specific kinase with nuclear restricted roles in the model fungus Aspergillus nidulans.By extending to A.nidulans the results of a synthetic lethal screen performed in Saccharomyces cerevisiae using the NIMA ortholog KIN3, we identi
Abstract Arthrofibrosis, or rigid contracture of major articular joints, is a significant morbidity of many neurodegenerative disorders.The pathogenesis depends on the mechanism and severity of the precipitating neuromuscular disorder.Most neuromuscular disorders, whether spastic or Specialty SMAW hypotonic, culminate in decreased joint range of mo
Abstract Ticks are obligate blood-sucking arachnid ectoparasites from the order Acarina, and many are notorious Cyclist Accessories - Gloves as vectors of a wide variety of zoonotic pathogens.However, the systematics of ticks in several genera is still controversial.The mitochondrial genome (mt-genome) has been widely used in arthropod phylogeny, m